BPC-157 (10mg vials)

Description

BPC-157 is a synthetic pentadecapeptide (15 amino acids) whose sequence is derived from a protein found in gastric juice. Peptide Partners supplies BPC-157 in 10mg vials for laboratory research into fibroblast and endothelial-cell signaling, including growth-factor receptor and nitric-oxide pathways.

BPC-157 specifications

Product Format	10mg vials
Vial Size	10mg
Vial Capacity	3 mL
Box Combinations	20mg, 50mg, 100mg, 200mg
Multi-vial Purity	99.66%
Purity Screening	PASSED
Doubly Validated	YES
Independently Tested	YES

Published research on BPC-157

The summaries below describe peer-reviewed literature for educational and reference purposes only. They do not describe uses of this product, which is sold for laboratory research only.

Pentadecapeptide BPC 157 Enhances the Growth Hormone Receptor Expression in Tendon Fibroblasts

Authors: Chung-Hsun Chang, Wen-Chung Tsai, Ya-Hui Hsu, and Jong-Hwei Su Pang
Source: https://www.mdpi.com/1420-3049/19/11/19066

In rat Achilles tendon fibroblasts, researchers measured growth hormone receptor mRNA and protein after BPC-157 exposure, along with cell proliferation (MTT assay), PCNA expression and JAK2 activation when growth hormone was added.

Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation

Authors: Ming-Jer Hsieh, Hsien-Ta Liu, Chao-Nin Wang, Hsiu-Yun Huang, Yuling Lin, Yu-Shien Ko, Jong-Shyan Wang, Vincent Hung-Shu Chang, Jong-Hwei S Pang
Source: https://pubmed.ncbi.nlm.nih.gov/27847966/

In human umbilical vein endothelial cells, BPC-157 increased tube formation and VEGFR2 expression and internalization, with time-dependent activation of the VEGFR2-Akt-eNOS pathway. Blocking endocytosis with dynasore prevented these effects.

Modulatory effects of BPC 157 on vasomotor tone and the activation of Src-Caveolin-1-endothelial nitric oxide synthase pathway

Authors: Ming-Jer Hsieh, Cheng-Hung Lee, Ho-Yen Chueh, Gwo-Jyh Chang, Hsiu-Yun Huang, Yuling Lin & Jong-Hwei S. Pang
Source: https://www.nature.com/articles/s41598-020-74022-y

Using isolated rat aorta and cultured vascular endothelial cells, researchers examined endothelium-dependent, nitric-oxide-mediated vasodilation, NO production, cell migration and phosphorylation of Src, Caveolin-1 and eNOS, along with Cav-1/eNOS binding by co-immunoprecipitation.

Storage and handling

BPC-157 is supplied for laboratory use. Store unopened vials cold and protected from light, and follow the storage notes on the vial label. Handle only in an appropriate laboratory setting by qualified personnel.

Research use only

This product is sold solely for in-vitro research and laboratory experimentation. It is not a drug, food, supplement or cosmetic, and is not for human or veterinary use. Information on this page is provided for educational purposes only. Purchasers must be qualified research professionals; see our Terms and Conditions.

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