Tesamorelin (10mg vials)

Description

Tesamorelin is a synthetic 44-amino-acid analog of growth hormone-releasing hormone (GHRH) with an N-terminal trans-3-hexenoyl modification. Peptide Partners supplies Tesamorelin in 10mg vials for laboratory research into GHRH receptor biology and analytical detection methods.

Tesamorelin specifications

Product Format	10mg vials
Vial Size	10mg
Vial Capacity	3 mL
Box Combinations	20mg, 50mg, 100mg, 200mg
Multi-vial Purity	99.81%
Endotoxin Screening	PASSED
Heavy Metals Screening	PASSED
Purity Screening	PASSED
Independently Tested	YES

Published research on Tesamorelin

The summaries below describe peer-reviewed literature for educational and reference purposes only. They do not describe uses of this product, which is sold for laboratory research only.

Qualitative identification of growth hormone-releasing hormones in human plasma by means of immunoaffinity purification and LC-HRMS/MS

Authors: Knoop A, Thomas A, Fichant E, Delahaut P, Schänzer W, Thevis M.
Source: https://pmc.ncbi.nlm.nih.gov/articles/PMC4830873/

Researchers developed and validated an immunoaffinity purification and nano-UHPLC-HRMS/MS method for simultaneously detecting four GHRH analogs, including tesamorelin, in human plasma. In-vitro incubations characterized tesamorelin’s metabolic stability, and the method was validated for specificity, recovery, detection limits and ion suppression.

Structural basis for activation of the growth hormone-releasing hormone receptor

Authors: Zhou F, Li JJ, Li XC, Jiang Y, Yang DH, Chen LN, Xu HE, Li MJ, Li XF.
Source: https://www.nature.com/articles/s41467-020-18945-0

This cryo-electron microscopy study resolved the structure of the human GHRH receptor bound to GHRH and the stimulatory G protein (Gs), identifying the ligand-binding site and key residues for receptor activation that are relevant to GHRH analogs such as tesamorelin.

Effects of tesamorelin on hepatic transcriptomic signatures in HIV-associated NAFLD

Authors: Fourman LT, Billingsley JM, Agyapong G, Ho Sui SJ, Feldpausch MN, Purdy J, Zheng I, McClure CM, Corey KE, Torriani M, Kleiner DE, Hadigan CM, Chung RT, Grinspoon SK.
Source: https://insight.jci.org/articles/view/140134

In a clinical research study, investigators performed RNA sequencing on liver biopsy samples and targeted plasma proteomics from participants receiving tesamorelin or placebo, reporting differences in hepatic gene sets related to inflammation, tissue remodeling and cell division.

Storage and handling

Tesamorelin is supplied for laboratory use. Store unopened vials cold and protected from light, and follow the storage notes on the vial label. Handle only in an appropriate laboratory setting by qualified personnel.

Research use only

This product is sold solely for in-vitro research and laboratory experimentation. It is not a drug, food, supplement or cosmetic, and is not for human or veterinary use. Information on this page is provided for educational purposes only. Purchasers must be qualified research professionals; see our Terms and Conditions.

Browse more Metabolics research peptides, review our testing standards, or see all research peptides.