Sermorelin (10mg vials)

Description

Sermorelin (GRF 1-29 NH2) is a synthetic peptide corresponding to the first 29 amino acids of growth hormone-releasing hormone (GHRH). Peptide Partners supplies Sermorelin in 10mg vials for laboratory research into GHRH-receptor signaling, peptide metabolism and analytical detection.

Sermorelin specifications

Product Format	10mg vials
Vial Size	10mg
Vial Capacity	3 mL
Box Combinations	20mg, 50mg, 100mg, 200mg
Multi-vial Purity	99.94%
Endotoxin Screening	PASSED
Heavy Metals Screening	PASSED
Purity Screening	PASSED
Independently Tested	YES

Published research on Sermorelin

The summaries below describe peer-reviewed literature for educational and reference purposes only. They do not describe uses of this product, which is sold for laboratory research only.

A potentially effective drug for patients with recurrent glioma: sermorelin

Authors: Chang Y, Huang R, Zhai Y, Huang L, Feng Y, Wang D, Chai R, Zhang W, Hu H.
Source: https://pmc.ncbi.nlm.nih.gov/articles/PMC8033379/

In U87 and LN229 glioma cell lines, sermorelin reduced cell proliferation in a concentration-dependent manner and was associated with cell-cycle changes. GO and KEGG analyses were used to relate a drug-resistance score to proliferation and immune-related gene signatures.

Advances in the detection of growth hormone releasing hormone synthetic analogs

Authors: Memdouh S, Gavrilović I, Ng K, Cowan D, Abbate V.
Source: https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/

This anti-doping study characterized the in-vitro metabolism of four synthetic GHRH analogs, including sermorelin, in fortified urine, identifying nineteen major metabolites to support analytical detection methods.

Qualitative identification of growth hormone-releasing hormones in human plasma by means of immunoaffinity purification and LC-HRMS/MS

Authors: Knoop A, Thomas A, Fichant E, Delahaut P, Schänzer W, Thevis M.
Source: https://pmc.ncbi.nlm.nih.gov/articles/PMC4830873/

Sermorelin incubated in human plasma was fully degraded within four hours. Researchers identified the metabolite GRF(3-29), formed when dipeptidyl peptidase-IV (DPP-IV) cleaves the N-terminal Tyr-Ala residues, and incorporated it into an LC-HRMS/MS detection method.

Storage and handling

Sermorelin is supplied for laboratory use. Store unopened vials cold and protected from light, and follow the storage notes on the vial label. Handle only in an appropriate laboratory setting by qualified personnel.

Research use only

This product is sold solely for in-vitro research and laboratory experimentation. It is not a drug, food, supplement or cosmetic, and is not for human or veterinary use. Information on this page is provided for educational purposes only. Purchasers must be qualified research professionals; see our Terms and Conditions.

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