CJC-1295 no DAC (10mg vials)

Description

CJC-1295 without DAC (also called modified GRF 1-29) is a synthetic 29-amino-acid GHRH analog with four amino-acid substitutions that increase resistance to enzymatic degradation. Peptide Partners supplies CJC-1295 no DAC in 10mg vials for laboratory research into GHRH-receptor pharmacology and analytical detection.

CJC-1295 no DAC specifications

Product Format	10mg vials
Vial Size	10mg
Vial Capacity	3 mL
Box Combinations	20mg, 50mg, 100mg, 200mg
Multi-vial Purity	99.77%
Endotoxin Screening	PASSED
Heavy Metals Screening	PASSED
Purity Screening	PASSED
Doubly Validated	YES
Independently Tested	YES

Published research on CJC-1295 no DAC

The summaries below describe peer-reviewed literature for educational and reference purposes only. They do not describe uses of this product, which is sold for laboratory research only.

An antibody-free, ultrafiltration-based assay for the detection of growth hormone-releasing hormones in urine at low pg/mL concentrations using nanoLC-HRMS/MS

Authors: Gilles Coppieters, Koen Deventer, Michaël Polet, Peter Van Eenoo, Péter Judák
Source: https://www.sciencedirect.com/science/article/abs/pii/S073170852200147

Researchers validated an antibody-free method combining ultrafiltration preconcentration with nanoLC-HRMS/MS to detect GHRH analogs, including CJC-1295, in urine at low pg/mL concentrations.

Advances in the detection of growth hormone releasing hormone synthetic analogs

Authors: Siham Memdouh, Ivana Gavrilović, Kelsey Ng, David Cowan, Vincenzo Abbate
Source: https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/

This study characterized the in-vitro metabolism of four synthetic GHRH analogs, including CJC-1295, in fortified human urine, identifying nineteen major metabolites and developing an LC-MS/MS method with detection limits of 1 ng/mL or lower.

Human Growth Hormone-Releasing Factor (hGRF)1–29-Albumin Bioconjugates Activate the GRF Receptor on the Anterior Pituitary in Rats: Identification of CJC-1295 as a Long-Lasting GRF Analog

Authors: Lucie Jetté, Roger Léger, Karen Thibaudeau, Corinne Benquet, Martin Robitaille, Isabelle Pellerin, Véronique Paradis, Pieter van Wyk, Khan Pham, Dominique P. Bridon
Source: https://academic.oup.com/endo/article/146/7/3052/2500187

Three maleimido derivatives of hGRF(1-29), including CJC-1295, were studied in vitro. When conjugated to human serum albumin they showed increased stability against DPP-IV and remained bioactive in a rat anterior pituitary cell GH-secretion assay.

Storage and handling

CJC-1295 no DAC is supplied for laboratory use. Store unopened vials cold and protected from light, and follow the storage notes on the vial label. Handle only in an appropriate laboratory setting by qualified personnel.

Research use only

This product is sold solely for in-vitro research and laboratory experimentation. It is not a drug, food, supplement or cosmetic, and is not for human or veterinary use. Information on this page is provided for educational purposes only. Purchasers must be qualified research professionals; see our Terms and Conditions.

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